The most common cause of a cystocele is childbirth. The muscles and ligaments in the pelvis around the vagina, which hold the vagina in place and support it, become stretched and weakened during labor and delivery. The more babies you deliver, the more the support tissues are stretched and weakened. Not everyone who has a baby will develop a cystocele. Some women have very strong supporting muscles and ligaments in the pelvis and may never have a problem. Women who have a Cesarean section delivery usually do not develop a cystocele.